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Caracterización de la pérdida de proteínas en líquido peritoneal, a través de dos sistemas de cierre temporal, en pacientes con abdomen abierto, atendidos en un hospital de tercer nivel de la ciudad de manizales en 2021
dc.contributor.advisor | Vergara Osorio, Giovanny | |
dc.contributor.author | Lizcano-González, Deisy Katherine | |
dc.contributor.editor | Florián Pérez, Maria Cristina | |
dc.date.accessioned | 2022-05-06T20:17:03Z | |
dc.date.available | 2022-05-06T20:17:03Z | |
dc.date.issued | 2022-05-06 | |
dc.identifier.uri | https://repositorio.ucaldas.edu.co/handle/ucaldas/17618 | |
dc.description | Ilustraciones | spa |
dc.description.abstract | spa:Objetivo: Algunos pacientes con patología quirúrgica abdominal que ingresan a la unidad de cuidado intensivo, requieren manejo con abdomen abierto. Esta condición genera una pérdida de proteínas desde la cavidad peritoneal expuesta, a través del líquido peritoneal. Se busca caracterizar la pérdida proteica según el cierre temporal abdominal empleado, etiología del abdomen abierto y describir la tendencia de la pérdida proteica. Diseño: estudio de cohortes, prospectivo, longitudinal. Ámbito: Unidad de cuidado intensivo quirúrgica de un hospital de alta complejidad. Pacientes: con patología quirúrgica de etiología inflamatoria, infecciosa u obstructiva que requirieron manejo con abdomen abierto. Intervenciones: recolección de muestras de líquido peritoneal intraoperatoria los días 1, 3, 5 y cuantificación durante este mismo periodo. Variables de interés principales: describir qué pacientes pierden más proteínas en líquido peritoneal, según la técnica de cierre temporal abdominal y según la etiología. Resultados: Los pacientes con abdomen abierto y uso de sistemas abdominales de presión negativa, pierden más proteínas en el líquido peritoneal. Esta pérdida no está influenciada por la etiología, ni por la infección con COVID-19 y disminuye gradualmente en el tiempo. Conclusiones: El abdomen abierto representa una fuente importante de pérdida de proteínas. Nuestra investigación determinó que según el sistema de cierre temporal, se pierden 25g de proteínas (3,8g de nitrógeno) por litro de líquido peritoneal para los pacientes con bolsa de Bogotá y 44 g/L (6.7g de nitrógeno) en pacientes con sistema ABThera. Por ello sugerimos que estas pérdidas proteicas deben ser tenidas en cuenta para realizar un adecuado soporte nutricional. Palabras clave: terapia de abdomen abierto; pérdida de proteínas; líquido abdominal; nutrición; Bolsa de Bogotá; Terapia de heridas con presión negativa; COVID-19. | spa |
dc.description.abstract | eng:Objective: Some patients with abdominal surgical pathology admitted to the intensive care unit require management with an open abdomen. This condition generates a loss of proteins from the exposed peritoneal cavity, through the peritoneal fluid. The aim is to characterize protein loss according to the temporary abdominal closure used, the etiology of the open abdomen and to describe the tendency of protein loss. Design: cohort, prospective, longitudinal study. Setting: Surgical intensive care unit of a high complexity hospital. Patients: with surgical pathology of inflammatory, infectious or obstructive etiology that required management with open abdomen. Interventions: collection of intraoperative peritoneal fluid samples on days 1, 3, 5 and quantification during this same period. Main variables of interest: describe which patients lose more protein in peritoneal fluid, according to the technique of temporary abdominal closure and according to the etiology. Results: Patients with an open abdomen and use of abdominal negative pressure systems lose more protein in the peritoneal fluid. This loss is not influenced by the etiology, nor by the infection with COVID-19 and gradually decreases over time. Conclusions: The open abdomen represents an important source of protein loss. Our research determined that according to the temporary closure system, 25g of protein (3.8g of nitrogen) are lost per liter of peritoneal fluid for patients with a Bogotá bag and 44g/L (6.7g of nitrogen) in patients with a system. ABThera. For this reason, we suggest that these protein losses should be considered in order to provide adequate nutritional support. Keywords: open abdomen therapy; protein loss; abdominal fluid; nutrition; Bogota bag; Negative pressure wound therapy; COVID-19. | eng |
dc.description.tableofcontents | 1. RESUMEN / 2. PLANTEAMIENTO DEL PROBLEMA / 3. ESTADO DEL ARTE / 4. MARCO TEÓRICO / 5. OBJETIVOS / 5.1 Objetivo general / 5.2 Objetivos específicos / 6. METODOLOGÍA / 6.1 Tipo de estudio / 6.2 Área de estudio / 6.3 Población / 6.4 Criterios de inclusión / 6.5 Criterios de exclusión / 6.6 Muestra / 6.7 Variables / 6.8 Técnicas e instrumentos de recolección de la información / 6.9 Análisis / 7. ASPECTOS ÉTICOS / 8. RESULTADOS /8.1 Reclutamiento de los participantes / 8.2 Descripción de los grupos de exposición / 8.3 Análisis multivariado / 9. DISCUSIÓN / 9.1 Fortalezas y debilidades / 9.2 Estudios futuros / 10. CONCLUSIONES / 11. BIBLIOGRAFÍA / 12. ANEXOS | spa |
dc.format.mimetype | application/pdf | spa |
dc.language.iso | eng | spa |
dc.language.iso | spa | spa |
dc.title | Caracterización de la pérdida de proteínas en líquido peritoneal, a través de dos sistemas de cierre temporal, en pacientes con abdomen abierto, atendidos en un hospital de tercer nivel de la ciudad de manizales en 2021 | spa |
dc.type | Trabajo de grado - Especialización | spa |
dc.description.degreelevel | Especialización médico - quirúrgica | spa |
dc.identifier.instname | Universidad de Caldas | spa |
dc.identifier.reponame | Repositorio Institucional Universidad de Caldas | spa |
dc.identifier.repourl | https://repositorio.ucaldas.edu.co/ | spa |
dc.publisher.faculty | Facultad de Ciencias para la Salud | spa |
dc.publisher.place | Manizales | spa |
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dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
dc.subject.proposal | Bolsa de Bogotá | spa |
dc.subject.proposal | Terapia de abdomen abierto | spa |
dc.subject.proposal | Pérdida de proteínas | spa |
dc.subject.proposal | Líquido abdominal | spa |
dc.subject.proposal | Nutrición | spa |
dc.subject.unesco | Ciencias médicas | |
dc.subject.unesco | Cirugía | |
dc.type.coar | http://purl.org/coar/resource_type/c_bdcc | spa |
dc.type.content | Text | spa |
dc.type.driver | info:eu-repo/semantics/masterThesis | spa |
dc.type.version | info:eu-repo/semantics/publishedVersion | spa |
oaire.version | http://purl.org/coar/version/c_ab4af688f83e57aa | spa |
oaire.accessrights | http://purl.org/coar/access_right/c_abf2 | spa |
dc.description.degreename | Especialista en Cirugía General | spa |
dc.publisher.program | Especialización en Cirugía General | spa |
dc.rights.coar | http://purl.org/coar/access_right/c_abf2 | spa |