@TECHREPORT{Sán_Des_2021, author = "Sánchez Rico, Yeny", title = "Descripción de características clínicas e histopatológicas renales de pacientes diabéticos con proteinuria en rango nefrótico", abstract = "eng: The present study describes the demographic, clinical and histopathological characteristics in a population of diabetic patients with 24-hour proteinuria in the nephrotic range; finding that the demographic characteristics were similar to other studies in other latitudes. Different types of lesions were also identified in the renal biopsy that were grouped into 3 groups according to the findings (diabetic nephropathy only, non-diabetic nephropathy only or a combination of both), finding that the most frequent was group 3, followed by group 2, contrary to what was considered years ago, in which it has been considered that proteinuria of any degree in a diabetic patient is only a consequence of diabetic nephropathy. Additionally, when making exploratory comparisons between these groups, we found that the value of proteinuria in 24 hours was much higher in the group that presented only diabetic nephropathy; however, this difference was not statistically significant, possibly due to the low number of patients in the study. present study. One of the variables in which we found statistically significant differences was in the time of diagnosis at the time of renal biopsy, being higher in the group with isolated diabetic nephropathy, similar to that found in the literature, this indicates that in patients with proteinuria in nephrotic range with a long time of evolution of diabetes could be more likely to find diabetic nephropathy as a finding in the renal biopsy. This is a study in which we intended to show and call attention to medical personnel who care for diabetic patients, that not all kidney alterations that these patients present will be secondary only to diabetic nephropathy, and that attention should be paid to the atypical manifestations and indications for renal biopsy that allow an early diagnosis that may impact on the treatment and prognosis of patients. We consider that it is necessary to carry out similar investigations in our environment, extending the time of collection of patients, which allows obtaining a larger sample, since it would allow better characterization, make associations and even carry out predictive models similar to those proposed in previous studies, which are adjusted to the characteristics of the Colombian population.", year = 2021, institution = "Universidad de Caldas", url = "https://repositorio.ucaldas.edu.co/handle/ucaldas/16485", }