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dc.contributor.advisorGonzález Gómez, Fernando Iván
dc.contributor.advisorGómez Montes, José Fernando
dc.contributor.advisorBOTERO BAENA, SANDRA MILENA
dc.contributor.authorToro López, Luis Ángel
dc.date.accessioned2022-01-14T18:20:52Z
dc.date.available2022-01-14T18:20:52Z
dc.date.issued2022-01-14
dc.identifier.urihttps://repositorio.ucaldas.edu.co/handle/ucaldas/17349
dc.descriptionIlustracionesspa
dc.description.abstractspa:Determinar la asociación entre dinapenia y mortalidad a un año en una cohorte de adultos mayores con fractura de cadera por fragilidad intervenidos quirúrgicamente en un centro hospitalario de tercer nivel de la ciudad de Manizales, Caldas. Metodología: Estudio observacional, prospectivo, longitudinal, en el que se evaluaron en el preoperatorio adultos mayores de 60 años con fractura de cadera por fragilidad entre mayo de 2019 y mayo de 2020. Se tomaron datos de fuerza de agarre por dinamometría a su ingreso, así como variables sociodemográficas, clínicas y funcionales, de laboratorio y de la intervención quirúrgica. Fueron seguidos durante la estancia hospitalaria hasta 1 año para determinar su estado vital, así como otros desenlaces durante el postoperatorio. Resultados: Fueron incluidos en el análisis 126 pacientes (mediana de 81 años de edad, mujeres 77%). La prevalencia de dinapenia en la cohorte fue de 71,4%. La mortalidad a 1 año en los dinapénicos fue de 42,2% y en los no dinapénicos de 8,3%, con una diferencia estadísticamente significativa (p = 0,000). El análisis multivariado de la asociación entre dinapenia y mortalidad, arrojó un OR ajustado a las covariables de 4,96 (IC 95% 1,359 - 18,084, p = 0,015); también se demostró asociación entre marcha previa dependiente con el desenlace mortalidad, con un OR ajustado de 4,83 (IC 95% 1,848 - 12,610, p = 0,001). Conclusión: En este estudio de adultos mayores con fractura de cadera por fragilidad, la dinapenia valorada preoperatoriamente fue un marcador predictor independiente de la mortalidad a 1 año.spa
dc.description.abstracteng:To determine the association between dynapenia and one-year mortality in a cohort of older adults with fragility hip fractures who underwent surgery in a tertiary care hospital in the city of Manizales, Caldas. Methodology: Observational, prospective, longitudinal study, in which adults over 60 years of age with a fragility hip fracture were evaluated preoperatively between May 2019 and May 2020. Grip strength data were taken by dynamometry upon admission, as well as sociodemographic, clinical and functional, laboratory and surgical intervention variables. They were followed up during their hospital stay for up to 1 year to determine their vital status, as well as other outcomes during the postoperative period. Results: 126 patients (median age 81 years, women 77%) were included in the analysis. The prevalence of dynapenia in the cohort was 71.4%. Mortality at 1 year in dynapenic patients was 42.2% and in non-dynapenic patients 8.3%, with a statistically significant difference (p = 0.000). The multivariate analysis of the association between dynapenia and mortality yielded an OR adjusted for covariates of 4.96 (95% CI 1.359 - 18.084, p = 0.015); An association was also shown between previous dependent gait and the mortality outcome, with an adjusted OR of 4.83 (95% CI 1.848 - 12.610, p = 0.001). Conclusion: In this study of older adults with fragility hip fracture, dynapenia assessed preoperatively was an independent predictor of 1-year mortality.eng
dc.description.tableofcontents1. Resumen / 2. Introducción / 2.1. Justificación / 2.2. Objetivo general / 2.3. Objetivos específicos / 2.4. Metodología / 3. Resultados / 4. Discusión / 5. Conclusiones y recomendaciones / 6. Bibliografía / 7. Anexosspa
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.language.isospaspa
dc.titleDinapenia como factor predictor de mortalidad a un año en una cohorte de adultos mayores con fractura de cadera por fragilidad intervenidos en un centro de tercer nivel de la ciudad de Manizales, Caldasspa
dc.typeTrabajo de grado - Especializaciónspa
dc.contributor.researchgroupGrupo de Investigación en Gerontología y Geriatría (Categoría A1)spa
dc.description.degreelevelEspecializaciónspa
dc.identifier.instnameUniversidad de Caldasspa
dc.identifier.reponameRepositorio Institucional Universidad de Caldasspa
dc.identifier.repourlhttps://repositorio.ucaldas.edu.co/spa
dc.publisher.facultyFacultad de Ciencias para la Saludspa
dc.publisher.placeManizalesspa
dc.relation.referencesChesser T, Chauhan G, Kelly M. Management of hip fractures in the elderly. Surg. 2016 Sep;34(9):440–3spa
dc.relation.referencesOrive M, Aguirre U, García-Gutiérrez S, Las Hayas C, Bilbao A, González N, et al. Changes in health-related quality of life and activities of daily living after hip fracture because of a fall in elderly patients: a prospective cohort study. Int J Clin Pract. 2015 Apr;69(4):491–500.spa
dc.relation.referencesCaillet P, Klemm S, Ducher M, Aussem A, Schott AM. Hip fracture in the elderly: A re-analysis of the EPIDOS study with causal Bayesian networks. PLoS One. 2015;10(3):1–12.spa
dc.relation.referencesChavarro D, Gutiérrez W, Cañón A. Correlación del estado funcional y nutricional en ancianos con fractura de cadera en un hospital de alta complejidad. Univ Medica. 2015;56(2):136–44.spa
dc.relation.referencesJackman JM, Watson JT. Hip Fractures in Older Men. Clin Geriatr Med. 2010 May;26(2):311–29.spa
dc.relation.referencesvon Friesendorff M, McGuigan FE, Wizert A, Rogmark C, Holmberg AH, Woolf AD, et al. Hip fracture, mortality risk, and cause of death over two decades. Osteoporos Int. 2016 Oct 12;27(10):2945–53.spa
dc.relation.referencesCummings-Vaughn LA, Gammack JK. Falls, Osteoporosis, and Hip Fractures. Med Clin North Am. 2011;95(3):495–506.spa
dc.relation.referencesLeBlanc KE, Muncie HL, LeBlanc LL. Hip fracture: diagnosis, treatment, and secondary prevention. Am Fam Physician. 2014 Jun 15;89(12):945–51.spa
dc.relation.referencesGialanella B, Ferlucci C, Monguzzi V, Prometti P, Unit R, Meas- FI, et al. Determinants of outcome in hip fracture: role of daily living activities. Eur J Phys Rehabil Med. 2015;51(3):253–60.spa
dc.relation.referencesvan Wissen J, van Stijn MFM, Doodeman HJ, Houdijk APJ. Mini nutritional assessment and mortality after hip fracture surgery in the elderly. J Nutr Health Aging. 2016;20(9):964–8.spa
dc.relation.referencesBurns A, Younger J, Morris J, Baldwin R, Tarrier N, Pendleton N, et al. Outcomes following hip fracture surgery: A 2-year prospective study. Am J Geriatr Psychiatry. 2014;22(8):838–44.spa
dc.relation.referencesDubljanin Raspopović E, Marić N, Nedeljković U, Ilić N, Tomanović Vujadinović S, Bumbaširević M. Do depressive symptoms on hospital admission impact early functional outcome in elderly patients with hip fracture? Psychogeriatrics. 2014;14(2):118–23.spa
dc.relation.referencesGialanella B, Ferlucci C, Monguzzi V, Prometti P. Determinants of functional outcome in hip fracture patients: The role of specific neuropsychiatric symptoms. Disabil Rehabil. 2015;37(6):517–22.spa
dc.relation.referencesCA M, Mus M, JP V, T van der P, DI V, LH E, et al. Dementia and delirium, the outcomes in elderly hip fracture patients. Clin Interv Aging. 2017;12:421– 30spa
dc.relation.referencesRodriguez-Fernandez P, Adarraga-Cansino D, Carpintero P. Effects of delayed hip fracture surgery on mortality and morbidity in elderly patients. Clin Orthop Relat Res. 2011;469(11):3218–21.spa
dc.relation.referencesOrive M, Anton-Ladislao A, García-Gutiérrez S, Las Hayas C, González N, Zabala J, et al. Prospective study of predictive factors of changes in pain and hip function after hip fracture among the elderly. Osteoporos Int. 2016;27(2):527–36.spa
dc.relation.referencesHong W, Cheng Q, Zhu X, Zhu H, Li H, Zhang X, et al. Prevalence of sarcopenia and its relationship with sites of fragility fractures in elderly Chinese men and women. PLoS One. 2015;10(9):1–10.spa
dc.relation.referencesOliveira A, Vaz C. The role of sarcopenia in the risk of osteoporotic hip fracture. Clin Rheumatol. 2015;34(10):1673–80.spa
dc.relation.referencesCruz-Jentoft AJ, Sayer AA. Sarcopenia. Lancet. 2019 Jun;393(10191):2636– 46.spa
dc.relation.referencesClark BC, Manini TM. Sarcopenia =/= Dynapenia. Journals Gerontol Ser A Biol Sci Med Sci. 2008 Aug 1;63(8):829–34.spa
dc.relation.referencesManini TM, Clark BC. Dynapenia and aging: An update. Journals Gerontol - Ser A Biol Sci Med Sci. 2012;67 A(1):28–40.spa
dc.relation.referencesClark BC, Manini TM. What is dynapenia? Nutrition. 2012;28(5):495–503.spa
dc.relation.referencesClark BC, Manini TM. Functional consequences of sarcopenia and dynapenia in the elderly. Curr Opin Clin Nutr Metab Care. 2010;13(3):271–6.spa
dc.relation.referencesUchida S, Kamiya K, Hamazaki N, Nozaki K, Ichikawa T, Nakamura T, et al. Prognostic utility of dynapenia in patients with cardiovascular disease. Clin Nutr. 2021;40(4):2210–8.spa
dc.relation.referencesSouweine J-S, Pasquier G, Kuster N, Rodriguez A, Patrier L, Morena M, et al. Dynapaenia and sarcopaenia in chronic haemodialysis patients: do muscle weakness and atrophy similarly influence poor outcome? Nephrol Dial Transplant. 2020;(December):1–11.spa
dc.relation.referencesBotsen D, Ordan MA, Barbe C, Mazza C, Perrier M, Moreau J, et al. Dynapenia could predict chemotherapy-induced dose-limiting neurotoxicity in digestive cancer patients. BMC Cancer. 2018;18(1):1–9.spa
dc.relation.referencesSelakovic I, Dubljanin-Raspopovic E, Markovic-Denic L, Marusic V, Cirkovic A, Kadija M, et al. Can early assessment of hand grip strength in older hip fracture patients predict functional outcome? PLoS One. 2019;14(8):1–10.spa
dc.relation.referencesDi Monaco M, Castiglioni C, De Toma E, Gardin L, Giordano S, Di Monaco R, et al. Handgrip strength but not appendicular lean mass is an independent predictor of functional outcome in hip-fracture women: A short-term prospective study. Arch Phys Med Rehabil. 2014;95(9):1719–24.spa
dc.relation.referencesDi Monaco M, Castiglioni C, De Toma E, Gardin L, Giordano S, Tappero R. Handgrip strength is an independent predictor of functional outcome in hipfracture women: A prospective study with 6-month follow-up. Med (United States). 2015;94(6):1–6.spa
dc.relation.referencesSavino E, Martini E, Lauretani F, Pioli G, Zagatti AM, Frondini C, et al. Handgrip strength predicts persistent walking recovery after hip fracture surgery. Am J Med. 2013;126(12):1068-1075.e1.spa
dc.relation.referencesGumieiro DN, Rafacho BPM, Gradella LM, Azevedo PS, Gaspardo D, Zornoff LAM, et al. Handgrip strength predicts pressure ulcers in patients with hip fractures. Nutrition. 2012;28(9):874–8.spa
dc.relation.referencesPérez-Rodríguez P, Rabes-Rodríguez L, Sáez-Nieto C, Alarcón TA, Queipo R, Otero-Puime Á, et al. Handgrip strength predicts 1-year functional recovery and mortality in hip fracture patients. Maturitas. 2020;141(October 2019):20–5.spa
dc.relation.referencesSuarez S, Pesantez RF, Diaz ME, Sanchez D, Tristancho LJ, Vanegas MV, et al. Impact on Hip Fracture Mortality after the Establishment of an Orthogeriatric Care Program in a Colombian Hospital. J Aging Health. 2017;29(3):474–88.spa
dc.relation.referencesGonzález FI, Moncada J, Quintero SMi, Quintero LP, Calderón D, Gómez JF. Comparación e implementación de un modelo de atención en ortogeriatría con la aplicación de un modelo “Fast Track” de fractura de cadera: Resultados de la prueba piloto. Asoc Colomb Gerontol y Geriatría. 2015;29(3).spa
dc.relation.referencesBenjumea AM, Curcio CL, Duque G, Gómez F. Dynapenia and sarcopenia as a risk factor for disability in a falls and fractures clinic in older persons. Open Access Maced J Med Sci. 2018;6(2):344–9.spa
dc.relation.referencesPeeters CMM, Visser E, Van De Ree CLP, Gosens T, Den Oudsten BL, De Vries J. Quality of life after hip fracture in the elderly: A systematic literature review. Injury. 2016;47(7):1369–82.spa
dc.relation.referencesBasu N, Natour M, Mounasamy V, Kates SL. Geriatric hip fracture management: keys to providing a successful program. Eur J Trauma Emerg Surg. 2016;42(5):565–9.spa
dc.relation.referencesTay YWA, Hong CC, Murphy D. Functional outcome and mortality in nonagenarians following hip fracture surgery. Arch Orthop Trauma Surg. 2014 Jun 30;134(6):765–72.spa
dc.relation.referencesYeung SSY, Reijnierse EM, Trappenburg MC, Hogrel JY, McPhee JS, Piasecki M, et al. Handgrip Strength Cannot Be Assumed a Proxy for Overall Muscle Strength. J Am Med Dir Assoc. 2018;19(8):703–9.spa
dc.relation.referencesKim WK, Kim D-K, Seo KM, Kang SH. Reliability and Validity of Isometric Knee Extensor Strength Test With Hand-Held Dynamometer Depending on Its Fixation: A Pilot Study. Ann Rehabil Med. 2014;38(1):84.spa
dc.relation.referencesLee SH, Gong HS. Measurement and interpretation of handgrip strength for research on sarcopenia and osteoporosis. J Bone Metab. 2020;27(2):85–96.spa
dc.relation.referencesRoberts HC, Denison HJ, Martin HJ, Patel HP, Syddall H, Cooper C, et al. A review of the measurement of grip strength in clinical and epidemiological studies: towards a standardised approach. Age Ageing. 2011 Jul;40(4):423– 9.spa
dc.relation.referencesCruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, et al. Sarcopenia: Revised European consensus on definition and diagnosis. Age Ageing. 2019;48(1):16–31.spa
dc.relation.referencesMahoney F, Barthel D. Functional evaluation: the Barthel Index. Md State Med J. 1965 Feb;14:61–5.spa
dc.relation.referencesCabañero-Martínez MJ, Cabrero-García J, Richart-Martínez M, MuñozMendoza CL. The Spanish versions of the Barthel index (BI) and the Katz index (KI) of activities of daily living (ADL): A structured review. Arch Gerontol Geriatr. 2009 Jul;49(1):e77–84.spa
dc.relation.referencesHolden MK, Gill KM, Magliozzi MR, Nathan J, Piehl-Baker L. Clinical Gait Assessment in the Neurologically Impaired. Phys Ther. 1984 Jan 1;64(1):35– 40.spa
dc.relation.referencesViosca E, Martínez JL, Almagro PL, Gracia A, González C. Proposal and Validation of a New Functional Ambulation Classification Scale for Clinical Use. Arch Phys Med Rehabil. 2005 Jun;86(6):1234–8.spa
dc.relation.referencesPostorino M, Marino C, Tripepi G, Zoccali C. Prognostic value of the New York Heart Association classification in end-stage renal disease. Nephrol Dial Transplant. 2007 Mar 8;22(5):1377–82.spa
dc.relation.referencesDoyle DJ, Goyal A, Bansal P, Garmon EH. American Society of Anesthesiologists Classification. StatPearls. 2021.spa
dc.relation.referencesVellas B, Guigoz Y, Garry PJ, Nourhashemi F, Bennahum D, Lauque S, et al. The mini nutritional assessment (MNA) and its use in grading the nutritional state of elderly patients. Nutrition. 1999 Feb;15(2):116–22.spa
dc.relation.referencesMuñoz Díaz B, Molina-Recio G, Romero-Saldaña M, Redondo Sánchez J, Aguado Taberné C, Arias Blanco C, et al. Validation (in Spanish) of the Mini Nutritional Assessment survey to assess the nutritional status of patients over 65 years of age. Fam Pract. 2019 Mar 20;36(2):172–8.spa
dc.relation.referencesFolstein MF, Folstein SE, McHugh PR. “Mini-mental state.” J Psychiatr Res. 1975 Nov;12(3):189–98.spa
dc.relation.referencesBlesa R, Pujol M, Aguilar M, Santacruz P, Bertran-Serra I, Hernández G, et al. Clinical validity of the ‘mini-mental state’ for Spanish speaking communities. Neuropsychologia. 2001 Jan;39(11):1150–7.spa
dc.relation.referencesYesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M, et al. Development and validation of a geriatric depression screening scale: A preliminary report. J Psychiatr Res. 1982 Jan;17(1):37–49.spa
dc.relation.referencesMartínez de la Iglesia J, Onís Vilches M, Dueñas Herrero R, Albert Colomer C, Aguado Taberné C, Luque Luque R. Versión española del cuestionario de Yesavage abreviado (GDS) para el despistaje de depresión en mayores de 65 años: adaptación y validación. Medifam. 2002;12(10):26–40.spa
dc.relation.referencesCharlson M, Szatrowski TP, Peterson J, Gold J. Validation of a combined comorbidity index. J Clin Epidemiol. 1994 Nov;47(11):1245–51.spa
dc.relation.referencesHolick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, et al. Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2011 Jul;96(7):1911–30.spa
dc.relation.referencesRijk JM, Roos PRKM, Deckx L, Van den Akker M, Buntinx F. Prognostic value of handgrip strength in people aged 60 years and older: A systematic review and meta-analysis. Geriatr Gerontol Int. 2016;16(1):5–20.spa
dc.relation.referencesXu BY, Yan S, Low LL, Vasanwala FF, Low SG. Predictors of poor functional outcomes and mortality in patients with hip fracture: A systematic review. BMC Musculoskelet Disord. 2019;20(1):1–9.spa
dc.relation.referencesGumieiro DN, Murino Rafacho BP, Buzati Pereira BL, Cavallari KA, Tanni SE, Azevedo PS, et al. Vitamin D serum levels are associated with handgrip strength but not with muscle mass or length of hospital stay after hip fracture. Nutrition. 2015;31(7–8):931–4.spa
dc.relation.referencesSmith T, Pelpola K, Ball M, Ong A, Myint PK. Pre-operative indicators for mortality following hip fracture surgery: A systematic review and metaanalysis. Age Ageing. 2014;43(4):464–71.spa
dc.relation.referencesCruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, et al. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010 Jul 1;39(4):412–23.spa
dc.relation.referencesKamel HK, Iqbal MA, Mogallapu R, Maas D, Hoffmann RG. Time to Ambulation after Hip Fracture Surgery: Relation to Hospitalization Outcomes. Journals Gerontol - Ser A Biol Sci Med Sci. 2003;58(11):1042–5.spa
dc.relation.referencesAprato A, Bechis M, Buzzone M, Bistolfi A, Daghino W, Massè A. No rest for elderly femur fracture patients: early surgery and early ambulation decrease mortality. J Orthop Traumatol. 2020;21(1):10–3.spa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.subject.proposalDinapeniaspa
dc.subject.proposalFuerza de agarrespa
dc.subject.proposalFractura de caderaspa
dc.subject.proposalAdulto mayorspa
dc.subject.proposalEnvejecimientospa
dc.subject.proposalMortalidadspa
dc.subject.unescoCiencias medicas
dc.subject.unescoMedicina clínica
dc.type.coarhttp://purl.org/coar/resource_type/c_bdccspa
dc.type.contentTextspa
dc.type.driverinfo:eu-repo/semantics/masterThesisspa
dc.type.versioninfo:eu-repo/semantics/publishedVersionspa
oaire.versionhttp://purl.org/coar/version/c_ab4af688f83e57aaspa
oaire.accessrightshttp://purl.org/coar/access_right/c_abf2spa
dc.description.degreenameEspecialista Medicina Interna - Geriatríaspa
dc.publisher.programEspecialización Medicina Interna - Geriatríaspa
dc.description.researchgroupMareo, inestabilidad, vértigo, caídas y fracturasspa
dc.rights.coarhttp://purl.org/coar/access_right/c_abf2spa


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