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Niveles de estradiol en niños y jóvenes y su relación con género, edad, presión arterial, lípidos plasmáticos y polimorfismo XbaI del receptor de estrógenos.

dc.contributor.authorAguillón Osma, Johannyspa
dc.contributor.authorBedoya Blandón, Ángela Maríaspa
dc.contributor.authorLoango Chamorro, Nelsyspa
dc.contributor.authorLandázuri, Patriciaspa
dc.date.accessioned2018-01-01 00:00:00
dc.date.accessioned2020-12-09T16:49:01Z
dc.date.available2018-01-01 00:00:00
dc.date.available2020-12-09T16:49:01Z
dc.date.issued2018-01-01
dc.identifier.issn1657-9550
dc.identifier.urihttps://doi.org/10.17151/biosa.2018.17.1.3
dc.identifier.urihttps://repositorio.ucaldas.edu.co/handle/ucaldas/12762
dc.description.abstractLa identificación de factores de riesgo para las enfermedades cardiovasculares (ECV) puede ayudar a prevenir su desarrollo. Las hormonas esteroides a través de sus receptores y las variaciones genéticas influyen sobre el metabolismo de los lípidos y la presión arterial, entre otras funciones. Métodos: Estudio descriptivo realizado en niños y adolescentes entre 8 y 18 años de edad. Objetivo: Determinar los niveles de estradiol y su relación con género, edad, presión arterial, lípidos plasmáticos y polimorfismo XbaI del receptor de estrógenos. Resultados: No se encontró relación estadística entre el polimorfismo XbaI y las concentraciones de estradiol, pero sí entre el polimorfismo y el perfil lipídico, de igual manera entre las concentraciones de esta hormona con triglicéridos y c-VLDL. Conclusión: Este trabajo evidencia la relación entre niveles de estrógenos, edad, presión sanguínea y lípidos plasmáticos, de igual forma demuestra una relación entre polimorfismo XbaI del ESR1 y los niveles de lípidos.spa
dc.description.abstractThe identification of risk factors for cardiovascular diseases (CVD), can help to prevent their development. The steroid hormones, through their receptors and genetic variations, influence the lipids metabolism and blood pressure among other functions. Methods: a descriptive study carried out with children and adolescents between 8 and 18 years old. Objective: To determine levels of estradiol and its relationship with gender, age, blood pressure, plasmatic lipids and polymorphism XbaI of the estrogens receptor. Results: No statistical relationship between polymorphism XbaI and concentrations of estradiol was found, but it was found between polymorphism and lipid profile and, in the same way, between the concentrations of the hormone and triglycerides and VLDL-c. Conclusion: This work shows a relationship between estrogen levels, age, blood pressure and plasma lipids as well as it shows a relationship between XbaI polymorphism of ESR1 and lipid levels.eng
dc.format.mimetypeapplication/pdfspa
dc.language.isospaspa
dc.publisherUniversidad de Caldasspa
dc.rightsDerechos de autor Johanny Aguillón Osmaspa
dc.rights.urihttps://creativecommons.org/licenses/by-nc-sa/4.0spa
dc.sourcehttps://revistasojs.ucaldas.edu.co/index.php/biosalud/article/view/2248spa
dc.subjectestrogens receptor 1eng
dc.subjectgenetic polymorphismeng
dc.subjectlipidseng
dc.subjectestradioleng
dc.subjectblood pressureeng
dc.subjectbody mass index (MeSH)eng
dc.subjectestrógenosspa
dc.subjectpolimorfismo genéticospa
dc.subjectlípidosspa
dc.subjectestradiolspa
dc.subjectpresión arterialspa
dc.subjectíndice de masa corporalspa
dc.titleNiveles de estradiol en niños y jóvenes y su relación con género, edad, presión arterial, lípidos plasmáticos y polimorfismo XbaI del receptor de estrógenos.spa
dc.typeSección Artículos Originalesspa
dc.typeArtículo de revistaspa
dc.typeJournal Articleeng
dc.identifier.doi10.17151/biosa.2018.17.1.3
dc.identifier.eissn2462-960X
dc.relation.citationendpage30
dc.relation.citationissue1spa
dc.relation.citationstartpage19
dc.relation.citationvolume17spa
dc.relation.ispartofjournalBiosaludspa
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dc.rights.creativecommonsEsta obra está bajo licencia internacional Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0.spa
dc.title.translatedEstradiol levels in children and young adolescents and its relation with gender, age, blood pressure, plasmatic lipids and polymorphism XbaI of estrogens receptor.eng
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dc.relation.citationeditionNúm. 1 , Año 2018 : Enero - Juniospa
dc.relation.bitstreamhttps://revistasojs.ucaldas.edu.co/index.php/biosalud/article/download/2248/2152
dc.type.coarversionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
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